pathogenicity island meaning in English
毒力岛
致病岛
Examples
- Virulence genes of pathogenic bacteria can be located on the chromosome where they may be organized as so - called pathogenicity island ( pai )
细菌毒力岛( pathogenicityisland ， pai )是指染色体上成簇排列的与细菌毒力密切相关的基因簇。 - The reason that different distribution frequency of hpi in various e . coli is unclear , either . as the high frequency distribution of hpi in eaggec , this study will focus on the following parts to discuss the function of yersiniae high - pathogenicity island in enteroaggregative e . coli
鉴于hpi在eaggec中的高频分布，本研究拟从eaggec菌株出发，着重从以下几个方面对eaggec携带的hpi毒力岛的功能进行了研究。 - The pathogenic strains of yersinia enterocolitica carry a 45 - kb high pathogenicity island ( hpi ) comprising iron - uptake - related genes such as irp1 - irp2 and fyua , which has been observed in 93 % of the 60 entero - adhesive e . coli { eaec } strains and 80 % of the e . coli isolated from blood samples
Hpi毒力岛功能核心区主要的结构基因为irp2 、 irp1和fyua ，是高度保守的。 irp2和irp1分别编码两种高分子量蛋白hmwp2和hmwp1 ， fyua编码鼠疫菌素受体。 - Many pai have been discovered in many pathogens to humans ( pathogenic e . coli , yersiniae spp . , salmonella spp . , vibrio cholerae et al . ) - among them , the pai of yersiniae which encodes siderophore yersiniabactin ( ybt ) system is designated high - pathogenicity island ( hpi ) . hpi is essential for the mouse virulence in yersiniae
其中，耶尔森菌中的一个与铁载体? ?耶尔森杆菌素( yersiniabactin , ybt )合成转运和调节有关的毒力岛被称为hpi毒力岛( high - pathogenicityisland ， hpi ) 。 - To dress the question if other virulence gene were present in this kind of strains , 152 of 436 irp2 - hybridized strains were re - confirmed and selected for this study . the virulence genes or putative virulence genes detected by pcr or hybridization include heat stable toxin ( st ) & heat labile toxin ( lt ) for enterotoxigenic e . coli ( etec ) , invasive plasmid antigen b ( ipab ) for enteroinvasive e . coli ( eiec ) , epec adherence factor ( eaf ) , epec secretion protein c ( espc ) for enteropathogenic e . coli ( epec ) , hemolysin ( hlya ) and shiga toxins ( sltl and slt2 ) for enterohaemorrhagic e . coli ( ehec ) and eaggec probe for entero - aggregative e . coli ( eaggec ) . the prra and yc73 genes of pathogenicity associated island ( pai ) of urepathogenic e . coli ( upec ) and " o " island 28 ( rtx 615 ) gene was also detected , the later was a newly discovered putative pathogenicity island in e . coli o157 : h7
为探讨携带小肠结肠炎耶尔森氏菌的hpi毒力岛的大肠杆菌是否具有其他已知的毒力基因，选取82株由原位杂交和pcr方法初筛irp2阳性的大肠杆菌菌株，进行在致泻性大肠杆菌的25个毒力基因的检测，包括肠产毒性大肠杆菌的热稳定毒素st和热不稳定毒素lt ，肠侵袭性大肠杆菌的侵袭蛋白b基因ipab ，肠致病性大肠杆菌的eaf 、 espc基因，肠出血性大肠杆菌的溶血素hly 、志贺毒素1 ( slt1 ) 、志贺毒素2 ( slt2 )基因，肠集聚性大肠杆菌的eaggec探针，以及在泌尿道致病性大肠杆菌和o157 ： h7大肠杆菌中新发现的毒力岛基因。